What Is IVF? What Are The Stages?

IVF treatment techniques have developed day by day, allowing them to enter our lives with new methods. These latest technological developments have been implemented based on the factors affecting the success rate of IVF treatment. To briefly mention these developments;


  • Testicular biopsy performed under the microscope (Microtese)
  • The technique of examining the embryos of couples with genetic problems and selecting healthy ones among them is PGD (Preimplantation Genetic Diagnosis)
  • The technique of thinning the embryo wall with the help of laser (Assisted Hatching)
  • The process of freezing embryos, sperm and eggs for later use (Frozen)
  • Technique applied to follow the development of the embryo under the camera and to select the healthy ones (Embryoscope)

Operation Details


STEP 1 (Initial examination and couple assessment)

The couple’s previous treatments and stories such as pregnancy, childbirth and miscarriage are listened to. If any, old analysis and examination results are evaluated.

  • Any surgical report or note
  • Sperm analysis
  • Female and male blood tests
  • Reports of previous treatments
  • Uterus movie
  • Chromosome analysis
  • Reports on other diseases

According to all these data, IVF treatment is planned and the day of treatment is determined.

STEP 2 (Stimulating the ovaries and creating eggs)
Egg-enhancing drugs (needle therapy) are applied to select good embryos in the ovaries and place them in the uterus and create a large number of eggs. Drug dosage and treatment process vary according to the patient’s age and egg reserve. It takes 8-12 days on average.
STEP 3 (Egg collection)
The developing eggs are collected under anesthesia and stored for fertilization under laboratory conditions. Meanwhile, the male also gives sperm. Just like in the sperm analysis, sperm is taken by masturbation. Sperm is taken from men who cannot give sperm with the micro TESE method. On average, this process takes half an hour. For the sperm sample to be given on the day of egg collection, the man should do a sexual abstinence for 2-4 days. This period should not be longer than 7 days.
STEP 4 IVF or microinjection (ICSI) application

Classical IVF-IVF (In Vitro Fertilization): It was a technique used in the early years of IVF, when microinjection had not yet been discovered. In recent years, since fertilization rates are lower than ICSI, it has become an undesirable IVF technique.

Microinjection (ICSI): It is the injection of sperm directly into the egg through a pipette under the microscope. Microinjection (ICSI) method is widely used in IVF treatment today. The purpose of microinjection is to increase fertilization to high rates by meeting the egg with the sperm one by one. Microinjection is widely used, especially in severe male infertility.

After the sperm taken from the man and the egg taken from the woman are combined under the microscope, they are followed up to the 6th day according to their development in the devices we call the incubator, which resembles the body environment.

STEP 5 (Embryo transfer)
Fertilized eggs stored in the laboratory for two to six days are painlessly placed in the uterus with the help of a special catheter. This process takes 5-10 minutes. Sexual intercourse is not recommended until the pregnancy test. Paracetamol group drugs can be used as pain relievers. You can take a bath in the form of a warm shower 1 day after the transfer.
STEP 6 (Pregnancy test)

A pregnancy test is performed 12 days after the transfer process, and it is learned whether pregnancy has occurred or not. This test is a blood test called BHCG in the blood that does not require fasting and satiety.

The patient is called for ultrasound control 1 week to 10 days after pregnancy is detected. Patients living outside the city or abroad, on the other hand, have their controls done at their location and provide information. Although it is a normal pregnancy after conception, we do not stop the drug support we use, especially in the first 3 months.


Operation Details
What awaits me on the first date?

For the purpose of reviewing previous fertility treatments at the first appointment and evaluating the most appropriate treatment and test options to make you achieve your dreams;

  • You will receive 4-dimensional Ultrasound examination for a comprehensive evaluation of the ovaries, hormone profile, general health status, screening for a health problem that may pose a risk to the mother and baby during pregnancy, genetic counseling and psychological support if necessary.
  • Planning for the evaluation of the uterine wall with ultrasound at the appropriate time in the middle of the menstrual period
  • Examination of the old uterine film HSG (uterine film), if any
  • You should apply with a sexual abstinence of at least 2 and at most 5 days from the day of your appointment for the evaluation of the male factor. When the general health status of the man, his life habits, hormonal status and semen analysis are evaluated, if a problem is observed, you will be contacted by a urologist.

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How long does IVF treatment take on average?

All stages of IVF treatment take an average of 15-18 days.

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My husband works very hard, do I need my husband to come every time?

No. Your partner may only come on the day of egg collection to give a sperm sample. However, your spouse’s sperm analysis should be seen and evaluated by our specialists. We can ask for consultation from our urology specialist when necessary. For this reason, it is necessary to make a detailed evaluation that the mother and father-to-be attend the first interview together. In this evaluation, after it is determined that the sperm analysis of the father-to-be is sufficient in in vitro fertilization, it is sufficient for the father-to-be to come only on the day of egg collection.

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Can I travel after embryo transfer?

On the same day as the plane.

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What should be considered when giving a sperm sample?
  • Hygiene is the most important issue in giving a sperm sample.
  • The sample container must be an identified and sterile container.
  • Care should be taken to ensure that no foreign substance is mixed into the semen sample, as it will affect sperm motility and vitality.
  • The entire ejaculate sample must be taken into the vessel without sample loss.
  • In case of sample loss, the laboratory must be informed.
  • The sample delivered to the laboratory is evaluated after 30 minutes of liquefaction and taken to the necessary preparation processes.

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Can I go shopping?

You can continue your daily social activities during your treatment. Eating, shopping, daily walks, going to the hairdresser, getting hair dyed, swimming in the sea will not affect your treatment process.

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Will I come for control every day during the treatment?

There is no need for daily control throughout the treatment. The first step of IVF treatment is the period of stimulating the ovaries by giving medication. This period lasts an average of 8-10 days. During this period, ultrasonography examinations are performed approximately 3 or 4 times. If necessary, hormone analyzes are performed. When the diameter of the follicle containing the egg cells reaches a sufficient size, the egg cracking needle is given and the egg collection process is performed 2 days later. The fertilization process of the eggs collected with the sperm sample taken from the male on the day of the egg collection process is performed. The embryo transfer is performed 2-5 days after the fertilization process, depending on the number of fertilized eggs.

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What should our sex life be like during IVF treatment?

There is no restriction on sexual intercourse during the stimulation period of the ovaries. However, there should be no sexual intercourse after the injection of the egg cracking injection. We do not recommend sexual intercourse until the embryo transfer and the result of the pregnancy test afterwards.

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